{"id":20377,"date":"2021-07-14T14:58:37","date_gmt":"2021-07-14T14:58:37","guid":{"rendered":"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/pracoviska\/ubev\/apu\/kbb\/publikacie\/"},"modified":"2022-11-13T21:31:51","modified_gmt":"2022-11-13T20:31:51","slug":"publikacie","status":"publish","type":"cpt_pracoviska","link":"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/pracoviska\/ustavy-pf\/ubev\/apu\/kbb\/publikacie\/","title":{"rendered":"Publik\u00e1cie"},"content":{"rendered":"

2021<\/strong>
Babin\u010d\u00e1k M., Jend\u017eelovsk\u00fd R., Ko\u0161uth J., Majern\u00edk M., Vargov\u00e1 J., Mikul\u00e1\u0161ek K., Zdr\u00e1hal Z., Fedoro\u010dko P. Death Receptor 5 (TNFRSF10B) Is Upregulated and TRAIL Resistance Is Reversed in Hypoxia and Normoxia in Colorectal Cancer Cell Lines after Treatment with Skyrin, the Active Metabolite of Hypericum spp. Cancers, 2021, 13, 1646. DOI: 10.3390\/cancers13071646 <\/a><\/p>\n

Hud\u00e1\u010dov\u00e1 M., Hamu\u013eakov\u00e1 S., Konko\u013eov\u00e1 E., Jend\u017eelovsk\u00fd R., Vargov\u00e1 J., \u0160evc J., Fedoro\u010dko P., Soukup O., Jano\u010dkov\u00e1 J., Ihnatova V., Ku\u010dera T., Bzonek P., Novakova N., Jun D., Junova L., Kor\u00e1be\u010dn\u00fd J., Ku\u010da K., Ko\u017eurkov\u00e1 M. Synthesis of new biscoumarin derivatives, in vitro cholinesterase inhibition, molecular modelling and antiproliferative effect in A549 human lung carcinoma cells. International Journal of Molecular Sciences, 2021, 22, 3830. DOI: 10.3390\/ijms22083830 <\/a><\/p>\n

Konko\u013eov\u00e1 E., Hud\u00e1\u010dov\u00e1 M., Hamu\u013eakov\u00e1 S., Jend\u017eelovsk\u00fd R., Vargov\u00e1 J., \u0160evc J., Fedoro\u010dko P., Ko\u017eurkov\u00e1 M. Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines. Molecules, 2021, 26, 1133. DOI: 10.3390\/molecules26041133<\/a><\/p>\n

Panigaj M, Dobrovolskaia MA, and Afonin KA. 2021: an immunotherapy odyssey and the rise of nucleic acid nanotechnology. Nanomedicine, 2021. DOI: 10.2217\/nnm-2021-0097<\/a><\/p>\n

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2020<\/strong>
Chandler M, Panigaj M, Johnson MB, and Afonin KA. Innate immune responses triggered by nucleic acids inspire the design of immunomodulatory nucleic acid nanoparticles (NANPs). Current Opinion in Biotechnology, 2020, 63: 8-15. DOI: 10.1016\/j.copbio.2019.10.011<\/a><\/p>\n

Chandler M, Panigaj M, Rolband LA, Afonin KA. Challenges to optimizing RNA nanostructures for large scale production and controlled therapeutic properties. Nanomedicine (Lond), 2020, 15(13):1331-40. DOI: 10.2217\/nnm-2020-0034<\/a><\/p>\n

Tonelli Gombalov\u00e1, Z.\u00a0 , Ko\u0161uth, J. , Alexovi\u010d Matia\u0161ov\u00e1, A., Zrub\u00e1kov\u00e1 , J., \u017de\u017eula, I., Giallongo, T.,\u00a0 Di Giulio, A.M., Carelli, S., Toma\u0161kov\u00e1, L., Daxnerov\u00e1, Z., \u0160evc, J. Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl\/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. Journal of Comparative Neurology, 2020, 528(15):2523-2550. DOI: 10.1002\/cne.24909<\/a><\/p>\n

Ko\u0161uth, J., Farka\u0161ovsk\u00e1, M., Mochnack\u00fd, F., Daxnerov\u00e1, Z., \u0160evc, J. Selection of reliable reference genes for analysis of gene expression in spinal cord during rat postnatal development and after injury. Brain Sciences, 2020, 10(1):6. DOI: 10.3390\/brainsci10010006<\/a><\/p>\n

Majern\u00edk M., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P. Potentiality, Limitations, and Consequences of Different Experimental Models to Improve Photodynamic Therapy for Cancer Treatment in Relation to Antiangiogenic Mechanism. Cancers, 2020, 12, 2118. DOI: 10.3390\/cancers12082118<\/a><\/p>\n

Macejov\u00e1 M., Sa\u010dkov\u00e1 V., Hradick\u00e1 P., Jend\u017eelovsk\u00fd R., Deme\u010dkov\u00e1 V., Fedoro\u010dko P. Combination of photoactive hypericin and Manumycin A exerts multiple anticancer effects on oxaliplatin-resistant colorectal cells. Toxicology in Vitro, 2020, 66, 104860. DOI: 10.1016\/j.tiv.2020.104860<\/a><\/p>\n

Suv\u00e1kov\u00e1 M., Majern\u00edk M., Jend\u017eelovsk\u00fd R., Hovan A., B\u00e1n\u00f3 G., Fedoro\u010dko P., Antal\u00edk M. In vitro study of disodium cromoglicate as a novel effective hydrotrope solvent for hypericin utilisation in photodynamic therapy. Journal of Photochemistry & Photobiology, B: Biology, 2020, 206, 111855. DOI: 10.1016\/j.jphotobiol.2020.111855<\/a><\/p>\n

Pipov\u00e1 Koko\u0161ov\u00e1 N., Kiskov\u00e1 T., Vilhanov\u00e1 K., \u0160tafurikov\u00e1 A., Jend\u017eelovsk\u00fd R., Ra\u010dekov\u00e1 E., \u0160majda B. Melatonin mitigates hippocampal and cognitive impairments caused by prenatal irradiation. European Journal of Neuroscience, 2020, 52(6):3575-3594. DOI: 10.1111\/ejn.14687<\/a><\/p>\n

Nunhart P., Konko\u013eov\u00e1 E., Janovec L., Jend\u017eelovsk\u00fd R., Vargov\u00e1 J., \u0160evc J., Matejov\u00e1 M., Milt\u00e1kov\u00e1 B., Fedoro\u010dko P., Kozurkova M. Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity. Bioorg. Chem., 2020, 94, 103393. DOI: 10.1016\/j.bioorg.2019.103393<\/a><\/p>\n

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2019<\/strong>
Majern\u00edk M., Jend\u017eelovsk\u00fd R., Babin\u010d\u00e1k M., Ko\u0161uth J., \u0160evc J., Tonelli Gombalov\u00e1 Z., Jend\u017eelovsk\u00e1 Z., Bur\u00edkov\u00e1 M., Fedoro\u010dko P. Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane. International Journal of Molecular Sciences, 2019, 20(12): 3004. DOI: 10.3390\/ijms20123004<\/a><\/p>\n

Jend\u017eelovsk\u00fd R., Jend\u017eelovsk\u00e1 Z., Kuch\u00e1rov\u00e1 B., Fedoro\u010dko P. Breast cancer resistance protein is the enemy of hypericin accumulation and toxicity of hypericin-mediated photodynamic therapy. Biomedicine and Pharmacotherapy, 2019, 109, 2173-2181. DOI: 10.1016\/j.biopha.2018.11.084<\/a><\/p>\n

Kuch\u00e1rov\u00e1 V., Kuch\u00e1r J., L\u00fck\u00f6ov\u00e1 A., Jend\u017eelovsk\u00fd R., Majern\u00edk M., Fedoro\u010dko P., Vilkov\u00e1 M., Radojevi\u0107 D. I., \u010comi\u0107 R. L., Poto\u010d\u0148\u00e1k I. Low-dimensional compounds containing bioactive ligands. Part XII: Synthesis, structures, spectra, in vitro antimicrobial and cytotoxic activities of zinc(II) complexes with halogenderivatives of quinoline-8-ol. Polyhedron, 2019, 170:447-457. DOI: 10.1016\/j.poly.2019.05.064<\/a><\/p>\n

Janockova J., Korabecny J., Plsikova J., Babkova K., Konkolova E., Kucerova D., Vargova J., Koval J., Jendzelovsky R., Fedorocko P., Kasparkova J., Brabec V., Rosocha J., Soukup O., Hamulakova S., Kuca K., Kozurkova M. In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers. Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34, 877-897. DOI: 10.1080\/14756366.2019.1593159<\/a><\/p>\n

Panigaj M, Johnson MB, Ke W, McMillan J, Goncharova EA, Chandler M, and Afonin KA. Aptamers as Modular Components of Therapeutic Nucleic Acid Nanotechnology, ACS Nano, 2019, 13(11): 12301-12321. DOI: 10.1021\/acsnano.9b06522<\/a><\/p>\n

Ke W, Hong E, Saito RF, Rangel MC, Wang J, Viard M, Richardson M, Khisamutdinov EF, Panigaj M, Dokholyan NV, Chammas R, Dobrovolskaia MA, Afonin KA. RNA-DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET, and transcriptional regulation of NF-\u03baB in human cells, Nucleic Acids Research, 2019, 47(3): 1350-1361. DOI: 10.1093\/nar\/gky1215<\/a><\/p>\n

Vranova E, Kopcsayova D, Kosuth J, Colinas M. Mutant-Based Model of Two Independent Pathways for Carotenoid-Mediated Chloroplast Biogenesis in Arabidopsis Embryos. Frontiers in Plant Science, 2019, 10, clanok 1034, DOI: 10.3389\/fpls.2019.0103<\/a>4<\/p>\n

Feckova B, Kimakova P, Ilkovicova L, Szentpeteriova E, Macejova M, Kosuth J, Zulli A, Debeljak N, Hudler P, Jasek K. Methylation of the first exon in the erythropoietin receptor gene does not correlate with its mRNA and protein level in cancer cells. BMC Genetics, 2019, 20, clanok 1, DOI: 10.1186\/s12863-018-0706-8<\/a><\/p>\n

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2018<\/strong>
Vargov\u00e1 J., Mike\u0161 J., Jend\u017eelovsk\u00fd R., Mike\u0161ov\u00e1 L., Kuch\u00e1rov\u00e1 B., \u010culka \u013d., Fedr R., Rem\u0161\u00edk J., Sou\u010dek K., Kozub\u00edk A., Fedoro\u010dko P.: Hypericin affects cancer side populations via competitive inhibition of BCRP. Biomedicine and Pharmacotherapy, 2018, 99: 511-522, 2018, DOI: 10.1016\/j.biopha.2018.01.074<\/a><\/p>\n

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2017<\/strong>
Halaburkov\u00e1 A., Jend\u017eelovsk\u00fd R., Kova\u013e J., Herceg Z., Fedoro\u010dko P., Ghantous A.: Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of cdnk1a. Clinical Epigenetics, 2017, 9:62. DOI: 10.1186\/s13148-017-0359-x<\/a><\/p>\n

Alexovi\u010d Matia\u0161ov\u00e1, A., \u0160evc, J., Tomori, Z., Gombalov\u00e1, Z., Gedrov\u00e1, \u0160., Daxnerov\u00e1, Z. Quantitative analyses of cellularity and proliferative activity reveals the dynamics of the central canal lining during postnatal development of rat. Journal of Comparative Neurology, 2017, 525(3):3963-707. DOI: 10.1002\/cne.24091<\/a><\/p>\n

Halman JR, Satterwhite E, Roark B, Chandler M, Viard M, Ivanina A, Bindewald E, Kasprzak WK, Panigaj M, Bui MN, Lu JS, Miller J, Khisamutdinov EF, Shapiro BA, Dobrovolskaia MA, Afonin KA. Functionally-interdependent shape-switching nanoparticles with controllable properties, Nucleic Acids Res., 2017, 45(4):2210-2220. DOI: 10.1093\/nar\/gkx008<\/a><\/p>\n

Salem O. M., Vilkov\u00e1 M., Jano\u010dkov\u00e1 J., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P., Imrich J., Ko\u017eurkov\u00e1 M. Synthesis, spectral characterization, DNA binding ability and anti-cancer screening of new acridine-based derivatives. Medicinal Chemistry Research, 2017, 26:2309\u20132321. DOI: 10.1007\/s00044-017-1931-9<\/a><\/p>\n

Sol\u00e1r P., Sa\u010dkov\u00e1 V., Hr\u010dkov\u00e1 G., Deme\u010dkov\u00e1 V., Kassayov\u00e1 M., Bojkov\u00e1 B., Mudro\u0148ov\u00e1 D., Gancar\u010d\u00edkov\u00e1 S., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P. Antitumor effect of the combination of manumycin A and Immodin is associated with antiplatelet activity and increased granulocyte tumor infiltration in a 4T1 breast tumor model. Oncology Reports, 2017, 37: 368-378. DOI: 10.3892\/or.2016.5265<\/a><\/p>\n

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2016<\/strong>
Gyur\u00e1szov\u00e1 K., Mike\u0161 J., Halaburkov\u00e1 A., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P. YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy. Photochemical & Photobiological Sciences, 2016, 15:812-821. DOI: 10.1039\/c5pp00438a<\/a><\/p>\n

Kassayov\u00e1 M., Bobrov N., Strojn\u00fd L., Orend\u00e1\u0161 P., Deme\u010dkov\u00e1 V. Jend\u017eelovsk\u00fd R., Kubatka P., Kiskov\u00e1 T., Kru\u017eliak P., Adamkov M., Bomba A., Fedoro\u010dko P. Anticancer and Immunomodulatory Effects of Lactobacillus plantarum LS\/07, Inulin and Melatonin in NMU-induced Rat Model of Breast Cancer. Anticancer Res, 2016, 36:2719-2728. PMID: 27272781<\/a><\/p>\n

\u0160emel\u00e1kov\u00e1 M., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P. Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells. Biomedicine and Pharmacotherapy, 2016, 81:38-47. DOI: 10.1016\/j.jphotobiol.2012.09.003<\/a><\/p>\n

Salem O. M., Vilkov\u00e1 M., Jano\u010dkov\u00e1 J., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P., \u017dileck\u00e1 E., Ka\u0161p\u00e1rkov\u00e1 J., Brabec V., Imrich J., Ko\u017eurkov\u00e1 M. New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds. International Journal of Biological Macromolecules, 2016, 86:690-700. DOI: 10.1016\/j.ijbiomac.2016.02.018<\/a><\/p>\n

Jend\u017eelovsk\u00e1 Z., Jend\u017eelovsk\u00fd R., Kuch\u00e1rov\u00e1 B., Fedoro\u010dko P.: Hypericin in the light and in the dark: Two sides of the same coin. Frontiers in Plant Science,2016, 7:560. DOI: 10.3389\/fpls.2016.00560<\/a><\/p>\n

Jend\u017eelovsk\u00fd R., Jend\u017eelovsk\u00e1 Z., Hi\u013eovsk\u00e1 L., Kova\u013e J., Mike\u0161 J., Fedoro\u010dko P. Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin. Toxicology Letters, 2016, 243:56-66. DOI: 10.1016\/j.toxlet.2015.12.002<\/a><\/p>\n

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2015<\/strong>
\u0160evc, J., Matia\u0161ov\u00e1, A., Smolekov\u00e1, I., Jend\u017eelovsk\u00fd, R., Mike\u0161, J., Tom\u00e1\u0161ov\u00e1, L., K\u00fatna, V., Daxnerov\u00e1, Z., Fedoro\u010dko, P. Peroral administration of 5-bromo-2 \u0301-deoxyuridine in drinking water is not reliable method for labeling of proliferating S-phase cells in rats. Journal of Pharmacological and Toxicological Methods, 2015, 74:33-39. DOI: 10.1016\/j.vascn.2015.05.012<\/a><\/p>\n

Macko J., Ori\u0148ak A., Ori\u0148akov\u00e1 R., Muhmann Ch., Petru\u0161 O., Harvanov\u00e1 D., Vargov\u00e1 J., Jend\u017eelovsk\u00fd R., Rado\u0148\u00e1k J., Fedoro\u010dko P., Arlinghaus H. F. New nanostructured nickel-polymer nanohybrids with improved surface hydrophobicity and effect on the living cells adhesion. Applied Surface Science, 2015, 355:553-561. DOI: 10.1016\/j.apsusc.2015.07.104<\/a><\/p>\n

Hi\u013eovsk\u00e1 L., Jend\u017eelovsk\u00fd R., Jend\u017eelovsk\u00e1 Z., Kova\u013e J, Fedoro\u010dko P. Downregulation of BCRP and anti-apoptotic proteins by proadifen (SKF-525A) is responsible for the enhanced mitoxantrone accumulation and toxicity in mitoxantrone-resistant human promyelocytic leukemia cells. International Journal of Oncology, 2015, 47:1572-1584. DOI: 10.3892\/ijo.2015.3116<\/a><\/p>\n

Kuch\u00e1rov\u00e1 B., Mike\u0161 J., Jend\u017eelovsk\u00fd R., Vargov\u00e1 J., Mike\u0161ov\u00e1 L., Jend\u017eelovsk\u00e1 Z., Kova\u013e J., Fedoro\u010dko P. Potentiation of hypericin-mediated photodynamic therapy cytotoxicity by MK-886: Focus on ABC transporters, GDF-15 and redox status. Photodiagnosis and Photodynamic therapy, 2015, 12:490-503. DOI: 10.1016\/j.pdpdt.2015.04.008<\/a><\/p>\n

Jano\u010dkov\u00e1 J. Pl\u0161\u00edkov\u00e1 J., Ka\u0161p\u00e1rkov\u00e1 J., Brabec V., Jend\u017eelovsk\u00fd R., Mike\u0161 J., Kova\u013e J., Hamu\u013e\u00e1kov\u00e1 S., Fedoro\u010dko P., Ku\u010da K., Ko\u017eurkov\u00e1 M. Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds. European Journal of Pharmaceutical Sciences, 2015, 76:192-202. DOI: 10.1016\/j.ejps.2015.04.023<\/a><\/p>\n

Jano\u010dkov\u00e1 J., Pl\u0161\u00edkov\u00e1 J., Koval‘ J., Jend\u017eelovsk\u00fd R., Mike\u0161 J., Ka\u0161p\u00e1rkov\u00e1 J., Brabec V., Hamu\u013eakov\u00e1 S., Fedoro\u010dko P., Ko\u017eurkov\u00e1 M. Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors. Bioorganic Chemistry, 2015, 59:168-176. DOI: 10.1016\/j.bioorg.2015.03.002<\/a><\/p>\n

Nagel R, Bernholz C, Vranova E, Kosuth J, Bergau N, Ludwig S, Wessjohann L, Gershenzon J, Tissier A, Schmidt A. Arabidopsis thaliana isoprenyl diphosphate synthases produce the C-25 intermediate geranylfarnesyl diphosphate. Plant Journal, 2015, 84(5), 847-859, DOI: 10.1111\/tpj.13064<\/a><\/p>\n

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2014<\/strong>
Matia\u0161ov\u00e1, A., \u0160evc, J., Mike\u0161, J., Jend\u017eelovsk\u00fd, R., Daxnerov\u00e1, Z., Fedoro\u010dko, P. Flow cytometric determination of 5-bromo-2 \u0301-deoxyuridine pharmacokinetics in blood serum after intraperitoneal administration to rats and mice. Histochemistry and Cell Biology, 2014, 142: 703-712. DOI: 10.1007\/s00418-014-1253-7<\/a><\/p>\n

\u0160evc, J., Matia\u0161ov\u00e1, A., K\u00fatna, V., Daxnerov\u00e1, Z. Evidence that the central canal lining of the spinal cord contributes to oligodendrogenesis during postnatal development and adulthood in intact rats, In: Journal of Comparative Neurology, 2014, 522(14):3194-207. DOI: 10.1002\/cne.23590 <\/a><\/p>\n

K\u00fatna, V., \u0160evc, J., Gombalov\u00e1, Z., Matia\u0161ov\u00e1, A., Daxnerov\u00e1 Z. Enigmatic cerebrospinal fluid-contacting neurons arise even after the termination of neurogenesis in the rat spinal cord during embryonic development and retain their immature-like characteristics until adulthood. Acta Histochemica, 2014, 116(1): 278-285. DOI: 10.1016\/j.acthis.2013.08.004 <\/a><\/p>\n

Kiskov\u00e1 T., Jend\u017eelovsk\u00fd R., Rentsen E., Maier-Salamon A., Koko\u0161ov\u00e1 N., Pap\u010dov\u00e1 Z., Mike\u0161 J., Orend\u00e1\u0161 P., Bojkov\u00e1 B., Kubatka P., Svoboda M., Kajo K., Fedoro\u010dko P., J\u00e4ger W., Ekmekcioglu C., Kassayov\u00e1 M., Thalhammer T. Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats. European Journal of Cancer Prevention, 2014, 23:506-13. DOI: 10.1097\/CEJ.0000000000000083 <\/a><\/p>\n

Jend\u017eelovsk\u00e1 Z., Jend\u017eelovsk\u00fd R., Hi\u013eovsk\u00e1 L., Kova\u013e J., Mike\u0161 J., Fedoro\u010dko P. Single pre-treatment with hypericin, a St. John\u2032swort secondary metabolite, attenuates cisplatin- and mitoxantrone-induced cell death in A2780, A2780cis and HL-60 cells. Toxicology in Vitro, 2014, 28:1259-1273. DOI: 10.1016\/j.tiv.2014.06.011 <\/a><\/p>\n

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2013<\/strong>
\u0160evc, J., Goldberg, D., van Gorp, S., Leerink, M., Juhas, S., Juhasova, J., Marsala, S., Hruska-Plochan, M., Hefferan, M.P., Motlik, J., Rypacek, F., Machova, L., Kakinohana, O., Santucci, C., Johe, K., Lukacova, N., Yamada, K., Bui, J.D., Marsala, M. Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: Effect on spinally grafted human neural precursor survival. Experimental Neurology, 2013, 248:85-99. DOI: 10.1016\/j.expneurol.2013.05.017 <\/a><\/p>\n

Kosuth J, Hrehorova D, Jaskolski M, Cellarova E. Stress-induced expression and structure of the putative gene hyp-1 for hypericin biosynthesis. Plant Cell Tissue and Ogan Culture, 2013, 114(2), 207-216, DOI: 10.1007\/s11240-013-0316-0<\/a><\/p>\n

Mike\u0161 J., Kova\u013e J., Jend\u017eelovsk\u00fd R., Mike\u0161ov\u00e1 L., \u0160inkorov\u00e1 Z., Fedoro\u010dko P. Procedure for improved cleaning of FACSAria cuvette flow cell. Cytometry PART A, Communication to the editor, 2013, 83A(6):523-527. DOI: 10.1002\/cyto.a.22293 <\/a><\/p>\n

Mike\u0161ov\u00e1 L., Mike\u0161 J., Valekov\u00e1 B., Gyur\u00e1szov\u00e1 K., \u010culka \u013d., Vargov\u00e1 J., Kova\u013e J., Fedoro\u010dko P. Conjunction of glutathione level, NAD(P)H\/FAD redox potential and hypericin content as a potential factor affecting colon cancer cells-resistance to photodynamic therapy with hypericin. Photodiagnosis and Photodynamic Therapy, 2013, 10:470-83. DOI: 10.1016\/j.pdpdt.2013.04.003 <\/a><\/p>\n

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2012<\/strong>
\u0160emel\u00e1kov\u00e1 M., Mike\u0161 J., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P. The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells. Journal of Photochemistry and Photobiology B: Biology, 2012, 117:115-125. DOI: 10.1016\/j.jphotobiol.2012.09.003<\/a><\/p>\n

Pl\u0161\u00edkov\u00e1 J., Janovec L., Kova\u013e J., Ungvarsk\u00fd J., Mike\u0161 J., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P., Imrich J., Kristi\u00e1n P., Ka\u0161p\u00e1rkov\u00e1 J., Brabec V., Ko\u017eurkov\u00e1 M. 3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents. European Journal of Medicinal Chemistry, 2012, 57:283-295. DOI: 10.1016\/j.ejmech.2012.09.020 <\/a><\/p>\n

Jend\u017eelovsk\u00fd R., Kova\u013e J., Mike\u0161 J., Pap\u010dov\u00e1 Z., Pl\u0161\u00edkov\u00e1 J., Fedoro\u010dko P. Inhibition of GSK-3\u03b2 reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells. Toxicology in Vitro, 2012, 26:775-782. DOI: 10.1016\/j.tiv.2012.05.014 <\/a><\/p>\n

Ba\u010dkorov\u00e1 M., Jend\u017eelovsk\u00fd R., Kello M., Ba\u010dkor M., Mike\u0161 J., Fedoro\u010dko P. Lichen secondary metabolites are responsible for induction of apoptosis in HT-29 and A2780 human cancer cell lines. Toxicology in Vitro, 2012, 26:462-468. DOI: 10.1016\/j.tiv.2012.01.017<\/a><\/p>\n

\u00a0<\/p>\n

2011<\/strong>
Mike\u0161 J., H\u00fd\u017e\u010falov\u00e1 M., Ko\u010d\u00ed L., Jend\u017eelovsk\u00fd R., Kova\u013e J., Vaculov\u00e1 A., Hofmanov\u00e1 J., Kozub\u00edk A., Fedoro\u010dko P. Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon danocarcinoma cells despite higher itracellular accumulation of hypericin. Photochemical & Photobiological Sciences, 2011, 10:626-632. DOI: 10.1039\/c0pp00359j<\/a><\/p>\n

Ba\u010dkorov\u00e1 M., Ba\u010dkor M., Mike\u0161 J., Jend\u017eelovsk\u00fd R., Fedoro\u010dko P. Variable responses of different human cancer cells to lichen compounds parietin, atranorin, usnic acid and gyrophoric acid. Toxicology in Vitro, 2011,25(1):37-44. DOI: 10.1016\/j.tiv.2010.09.004<\/a><\/p>\n

\u0160evc J, Daxnerov\u00e1 Z, Ha\u0148ov\u00e1 V, Koval‘ J. Novel observations on the origin of ependymal cells in the ventricular zone of the rat spinal cord. Acta Histochem., 2011, 113:156-62. DOI: 10.1016\/j.acthis.2009.09.007<\/a><\/p>\n

Kosuth J, Smelcerovic A, Borsch T, Zuehlke S, Karppinen K, Spiteller M, Hohtola A, Cellarova E. The hyp-1 gene is not a limiting factor for hypericin biosynthesis in the genus Hypericum. Functional Plant Biology, 2011, 38(1):35-43, DOI: 10.1071\/FP10144<\/a><\/p>\n

\u00a0<\/p>\n

2010<\/strong>
Kello M., Mike\u0161 J., Jend\u017eelovsk\u00fd R., Kova\u013e J., Fedoro\u010dko P. PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT. Photochemical & Photobiological Sciences, 2010, 9:1244-1251. DOI: 10.1039\/c0pp00085j<\/a><\/p>\n

Kova\u013e J., Mike\u0161 J., Jend\u017eelovsk\u00fd R., Kello M., Sol\u00e1r P., Fedoro\u010dko P. Degradation of HER2 receptor through hypericin-mediated photodynamic therapy. Photochemistry and Photobiology, 2010, 86(1):200-205. 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