{"id":70844,"date":"2024-07-10T13:04:14","date_gmt":"2024-07-10T12:04:14","guid":{"rendered":"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/?post_type=cpt_aktuality&#038;p=70844"},"modified":"2024-07-10T13:37:57","modified_gmt":"2024-07-10T12:37:57","slug":"ustav-chemickych-vied-na-obalke-casopisu-dalton-transactions-q1","status":"publish","type":"cpt_aktuality","link":"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/actuality\/ustav-chemickych-vied-na-obalke-casopisu-dalton-transactions-q1\/","title":{"rendered":"\u00dastav chemick\u00fdch vied na ob\u00e1lke \u010dasopisu Dalton Transactions (Q1)"},"content":{"rendered":"\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<style>.kadence-column70844_6219af-67 > .kt-inside-inner-col{padding-top:var(--global-kb-spacing-xs, 1rem);padding-right:var(--global-kb-spacing-xs, 1rem);padding-left:var(--global-kb-spacing-xs, 1rem);}.kadence-column70844_6219af-67 > .kt-inside-inner-col,.kadence-column70844_6219af-67 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column70844_6219af-67 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column70844_6219af-67 > .kt-inside-inner-col{flex-direction:column;}.kadence-column70844_6219af-67 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column70844_6219af-67 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column70844_6219af-67{position:relative;}@media all and (max-width: 1024px){.kadence-column70844_6219af-67 > .kt-inside-inner-col{flex-direction:column;}}@media all and (max-width: 767px){.kadence-column70844_6219af-67 > .kt-inside-inner-col{flex-direction:column;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column70844_6219af-67\"><div class=\"kt-inside-inner-col\">\n<p class=\"has-text-align-justify\">Oblas\u0165 modernej medic\u00edny \u010del\u00ed \u010doraz viac nov\u00fdm v\u00fdzvam v boji proti multirezistencii patog\u00e9nnych mikroorganizmov ako aj rakovinov\u00fdch buniek, ktor\u00e9 vyvol\u00e1vaj\u00fa z\u00e1va\u017en\u00e9 a\u00a0\u017eivot ohrozuj\u00face ochorenia po celom svete.<\/p>\n\n\n<style>.kb-row-layout-id70844_3c5485-ad > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id70844_3c5485-ad > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id70844_3c5485-ad > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, calc(40% - ((var(--global-kb-gap-md, 2rem) * 1 )\/2))) minmax(0, calc(60% - ((var(--global-kb-gap-md, 2rem) * 1 )\/2)));}.kb-row-layout-id70844_3c5485-ad > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id70844_3c5485-ad > .kt-row-column-wrap{grid-template-columns:repeat(2, minmax(0, 1fr));}}@media all and (max-width: 767px){.kb-row-layout-id70844_3c5485-ad > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id70844_3c5485-ad alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-right-golden kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column70844_273625-04 > .kt-inside-inner-col,.kadence-column70844_273625-04 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column70844_273625-04 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column70844_273625-04 > .kt-inside-inner-col{flex-direction:column;}.kadence-column70844_273625-04 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column70844_273625-04 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column70844_273625-04{position:relative;}@media all and (max-width: 1024px){.kadence-column70844_273625-04 > .kt-inside-inner-col{flex-direction:column;}}@media all and (max-width: 767px){.kadence-column70844_273625-04 > .kt-inside-inner-col{flex-direction:column;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column70844_273625-04\"><div class=\"kt-inside-inner-col\"><style>.kb-image70844_9d0930-33 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image70844_9d0930-33 size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"467\" height=\"600\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/10\/2024\/07\/Dalton-Transactions_Vargova.png\" alt=\"\" class=\"kb-img wp-image-70845\" srcset=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/10\/2024\/07\/Dalton-Transactions_Vargova.png 467w, https:\/\/www.upjs.sk\/app\/uploads\/sites\/10\/2024\/07\/Dalton-Transactions_Vargova-234x300.png 234w\" sizes=\"(max-width: 467px) 100vw, 467px\" \/><\/figure>\n<\/div><\/div>\n\n\n<style>.kadence-column70844_7c95f7-ff > .kt-inside-inner-col,.kadence-column70844_7c95f7-ff > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column70844_7c95f7-ff > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column70844_7c95f7-ff > .kt-inside-inner-col{flex-direction:column;}.kadence-column70844_7c95f7-ff > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column70844_7c95f7-ff > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column70844_7c95f7-ff{position:relative;}@media all and (max-width: 1024px){.kadence-column70844_7c95f7-ff > .kt-inside-inner-col{flex-direction:column;}}@media all and (max-width: 767px){.kadence-column70844_7c95f7-ff > .kt-inside-inner-col{flex-direction:column;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column70844_7c95f7-ff\"><div class=\"kt-inside-inner-col\">\n<p class=\"has-text-align-justify\">Pracovn\u00fd t\u00edm <strong><a href=\"https:\/\/www.upjs.sk\/PF\/zamestnanec\/zuzana.vargova\/\" class=\"ek-link\">prof. RNDr. Zuzany Vargovej, Ph.D.<\/a><\/strong> na Katedre anorganickej ch\u00e9mie <strong><a href=\"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/pracoviska\/ustavy-pf\/uchv\/\" class=\"ek-link\">\u00dastavu chemick\u00fdch vied<\/a><\/strong> Pr\u00edrodovedeckej fakulty UPJ\u0160 je zameran\u00fd na\u00a0synt\u00e9zu a\u00a0charakteriz\u00e1ciu nov\u00fdch, biodostupn\u00fdch preva\u017ene strieborn\u00fdch komplexn\u00fdch zl\u00fa\u010den\u00edn, ke\u010f\u017ee samotn\u00e9 strieborn\u00e9 i\u00f3ny maj\u00fa osved\u010den\u00e9 antimikrobi\u00e1lne a\u00a0v\u00a0posledn\u00fdch rokoch zisten\u00e9 aj antineoplastick\u00e9 \u00fa\u010dinky. V\u00fdskumn\u00e1 skupina v\u00a0spolupr\u00e1ci s Univerzitou Karlovou v Prahe, Univerzitou veterin\u00e1rskeho lek\u00e1rstva a farm\u00e1cie v\u00a0Ko\u0161iciach, \u00dastavom fyzik\u00e1lnej ch\u00e9mie \u010ceskej akad\u00e9mie vied v\u00a0Prahe a\u00a0Lek\u00e1rskou fakultou UPJ\u0160 pripravila a\u00a0charakterizovala dve nov\u00e9 strieborn\u00e9 koordina\u010dn\u00e9 zl\u00fa\u010deniny, ktor\u00e9 vykazuj\u00fa s\u013eubn\u00e9 <em>in vitro<\/em> a\u00a0<em>in ovo<\/em> v\u00fdsledky, ktor\u00e9 boli publikovan\u00e9 v\u00a0prest\u00ed\u017enom vedeckom karentovanom \u010dasopise <strong>Dalton Transactions (Q1)<\/strong>. Nov\u00fd experiment\u00e1lno-teoretick\u00fd pr\u00edstup ku korel\u00e1cie chemick\u00fdch, biologick\u00fdch a\u00a0farmaceutick\u00fdch parametrov zaujal redak\u010dn\u00fd t\u00edm \u010dasopisu nato\u013eko, \u017ee sa rozhodli poskytn\u00fa\u0165 <strong><em>priestor na prezent\u00e1ciu pr\u00e1ce aj na ob\u00e1lke \u010dasopisu. <\/em><\/strong>Na z\u00e1klade experiment\u00e1lnych v\u00fdsledkov tejto je mo\u017en\u00e9 skon\u0161tatova\u0165, \u017ee pripraven\u00e9 strieborn\u00e9 komplexy AgPro a AgHyp v n\u00edzkej koncentr\u00e1cii efekt\u00edvne zastavuj\u00fa rast v\u00a0bakt\u00e9ri\u00ed <em>B. cereus<\/em> a\u00a0<em>S. aureus<\/em>, pri\u010dom ich antibakteri\u00e1lna aktivita je porovnate\u013en\u00e1 s\u00a0\u00fa\u010dinkom lie\u010diva sulfadiz\u00ednu strieborn\u00e9ho.<\/p>\n<\/div><\/div>\n\n<\/div><\/div>\n\n\n<p class=\"has-text-align-justify\"> Z\u00e1rove\u0148 protirakovinov\u00e1 aktivita uveden\u00fdch strieborn\u00fdch zl\u00fa\u010den\u00edn bola dokonca pri rakovinovej l\u00ednii MDA-MB-231 v\u00fdrazne vy\u0161\u0161ia ako aktivita s\u00fa\u010dasne pou\u017e\u00edvan\u00e9ho lie\u010diva \u2013 cisplatiny.\u00a0Okrem in\u00e9ho \u0161t\u00fadium potenci\u00e1lnej vasoirit\u00e1cie pripraven\u00fdch strieborn\u00fdch komplexov preuk\u00e1zalo bezpe\u010dnos\u0165 pri intraven\u00f3znom pod\u00e1van\u00ed t\u00fdchto l\u00e1tok.<\/p>\n\n\n\n<p class=\"has-text-align-justify\">Kuzderov\u00e1, G., Sovov\u00e1, S., Rendo\u0161ov\u00e1, M., Gyepes, R., Sabolov\u00e1, D., Ko\u017e\u00e1rov\u00e1, I., Bal\u00e1\u017eov\u00e1, \u013d., Vilkov\u00e1, M., Kello, M., \u00a0Li\u0161ka, A., Vargov\u00e1, Z. (2024). Influence of proline and hydroxyproline as antimicrobial and anticancer peptide components on the silver(i) ion activity: structural and biological evaluation with a new theoretical and experimental SAR approach. <\/p>\n\n\n<style>.wp-block-kadence-column.kb-section-dir-horizontal > .kt-inside-inner-col > .kt-info-box70844_3045f7-a5 .kt-blocks-info-box-link-wrap{max-width:unset;}.kt-info-box70844_3045f7-a5 .kt-blocks-info-box-link-wrap{border-top:0px solid var(--global-palette7, #eeeeee);border-right:0px solid var(--global-palette7, #eeeeee);border-bottom:0px solid var(--global-palette7, #eeeeee);border-left:0px solid var(--global-palette7, #eeeeee);border-top-left-radius:30px;border-top-right-radius:30px;border-bottom-right-radius:30px;border-bottom-left-radius:30px;background:#ffffff;padding-top:var(--global-kb-spacing-xs, 1rem);padding-right:var(--global-kb-spacing-xs, 1rem);padding-bottom:var(--global-kb-spacing-xs, 1rem);padding-left:var(--global-kb-spacing-xs, 1rem);}.kt-info-box70844_3045f7-a5 .kadence-info-box-icon-container .kt-info-svg-icon, .kt-info-box70844_3045f7-a5 .kt-info-svg-icon-flip, .kt-info-box70844_3045f7-a5 .kt-blocks-info-box-number{font-size:20px;}.kt-info-box70844_3045f7-a5 .kt-blocks-info-box-media{color:#008338;border-radius:200px;border-top-width:0px;border-right-width:0px;border-bottom-width:0px;border-left-width:0px;padding-top:9px;padding-right:9px;padding-bottom:9px;padding-left:9px;margin-top:0px;margin-right:5px;margin-bottom:0px;margin-left:0px;}.kt-info-box70844_3045f7-a5 .kt-blocks-info-box-media .kadence-info-box-image-intrisic img{border-radius:200px;}.kt-info-box70844_3045f7-a5 .kt-blocks-info-box-link-wrap:hover .kt-blocks-info-box-media{color:#C19152;}.kt-info-box70844_3045f7-a5 .kt-infobox-textcontent h2.kt-blocks-info-box-title{padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-top:5px;margin-right:0px;margin-bottom:10px;margin-left:0px;}.kt-info-box70844_3045f7-a5 .kt-infobox-textcontent .kt-blocks-info-box-text{color:#000000;}.kt-info-box70844_3045f7-a5 .kt-blocks-info-box-learnmore{background:transparent;border-width:0px 0px 0px 0px;padding-top:4px;padding-right:8px;padding-bottom:4px;padding-left:8px;margin-top:10px;margin-right:0px;margin-bottom:10px;margin-left:0px;}@media all and (max-width: 1024px){.kt-info-box70844_3045f7-a5 .kt-blocks-info-box-link-wrap{border-top:0px solid var(--global-palette7, #eeeeee);border-right:0px solid var(--global-palette7, #eeeeee);border-bottom:0px solid var(--global-palette7, #eeeeee);border-left:0px solid var(--global-palette7, #eeeeee);}}@media all and (max-width: 767px){.kt-info-box70844_3045f7-a5 .kt-blocks-info-box-link-wrap{border-top:0px solid var(--global-palette7, #eeeeee);border-right:0px solid var(--global-palette7, #eeeeee);border-bottom:0px solid var(--global-palette7, #eeeeee);border-left:0px solid var(--global-palette7, #eeeeee);}}<\/style>\n<div class=\"wp-block-kadence-infobox kt-info-box70844_3045f7-a5\"><a class=\"kt-blocks-info-box-link-wrap info-box-link kt-blocks-info-box-media-align-left kt-info-halign-left\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/doi.org\/10.1039\/D4DT00389F\"><div class=\"kt-blocks-info-box-media-container\"><div class=\"kt-blocks-info-box-media kt-info-media-animate-none\"><div class=\"kadence-info-box-icon-container kt-info-icon-animate-none\"><div class=\"kadence-info-box-icon-inner-container\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fe_externalLink kt-info-svg-icon\"><svg viewBox=\"0 0 24 24\"  fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M18 13v6a2 2 0 0 1-2 2H5a2 2 0 0 1-2-2V8a2 2 0 0 1 2-2h6\"\/><polyline points=\"15 3 21 3 21 9\"\/><line x1=\"10\" y1=\"14\" x2=\"21\" y2=\"3\"\/><\/svg><\/span><\/div><\/div><\/div><\/div><div class=\"kt-infobox-textcontent\"><p class=\"kt-blocks-info-box-text\"><strong><em>Dalton Trans.<\/em><\/strong>, 2024, <strong>53<\/strong>, 10834-10850.<\/p><\/div><\/a><\/div>\n\n\n\n<p> <strong>.<\/strong><\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Pracovn\u00fd t\u00edm prof. RNDr. Zuzany Vargovej, Ph.D. na Katedre anorganickej ch\u00e9mie \u00dastavu chemick\u00fdch vied Pr\u00edrodovedeckej fakulty UPJ\u0160 je zameran\u00fd na synt\u00e9zu a charakteriz\u00e1ciu nov\u00fdch, biodostupn\u00fdch preva\u017ene strieborn\u00fdch komplexn\u00fdch zl\u00fa\u010den\u00edn, ke\u010f\u017ee samotn\u00e9 strieborn\u00e9 i\u00f3ny maj\u00fa osved\u010den\u00e9 antimikrobi\u00e1lne a v posledn\u00fdch rokoch zisten\u00e9 aj antineoplastick\u00e9 \u00fa\u010dinky.<\/p>\n","protected":false},"author":25,"featured_media":70861,"template":"","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[],"tags":[63],"tax_aktuality":[],"acf":{"acf_link_na_externy_obsah":"","poradie_clanku":0},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u00dastav chemick\u00fdch vied na ob\u00e1lke \u010dasopisu Dalton Transactions (Q1) - Pr\u00edrodovedeck\u00e1 fakulta | UPJ\u0160<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/actuality\/ustav-chemickych-vied-na-obalke-casopisu-dalton-transactions-q1\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00dastav chemick\u00fdch vied na ob\u00e1lke \u010dasopisu Dalton Transactions (Q1) - Pr\u00edrodovedeck\u00e1 fakulta | UPJ\u0160\" \/>\n<meta property=\"og:description\" content=\"Pracovn\u00fd t\u00edm prof. 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