Our colleagues from the CasProt Project – Assoc. Prof. Erik Sedlák, Dr. Mária Tomková and Dr. Veronika Talafová, participated in the XXVI. Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology with the cooperation of the Austrian and German Biochemical Section which took place in České Budejovice, Czech Republic from August 29 to September 1, 2021. This scientific event focused on the presentation of the latest scientific knowledge in the field of Biochemistry and Molecular Biology. Assoc. Prof. Erik Sedlák had a lecture in the section Enzymes, Coenzymes, Inhibitors on the topic: “Flavon cofactor in AsLOV2 domain as efficient singlet oxygen producer“ and expressed gratitude for the CasProt project. He was also a member of the Committee of the Slovak Society for Biochemistry and Molecular Biology in meetings with members of the Czech Committee and had an opportunity to discuss scientific cooperation as well as a joint educational program Biophysics, respectively Biochemistry.
Participation in the conference was associated with the presentation of research results in the form of a poster and also served to gain knowledge and new working contacts in the field of experimental methods based on protein selection. Dr. Veronika Talafová presented her results during the poster sessions, poster: Self-assembly kinetic model of recombinant spider silk protein eADF4(C16).
Dr. Maria Tomkova had also a presentation on the optimization of preparation of functional ribosomes, which are necessary for ribosome display of proteins in the poster session, poster: Preparation of a ribosome extract for in vitro protein evolution through ribosome display. The results of the study are widely used in optimizing the evolutionary techniques of modified proteins (GPCR, dehalogenase, staphylokinase, etc.) with improved properties such as catalytic efficiency, stability and solubility (important for storage capacity) of proteins.
