GenICa<\/em>\u201d<\/a> \n<\/strong>Zodpovedn\u00e1 osoba: RNDr. Martina \u0160emel\u00e1kov\u00e1, PhD. \nDoba realiz\u00e1cie projektu: september 2023 – september 2024<\/p>\nVEGA\u00a0 1\/0312\/14: \u00daloha polymorfizmov kandid\u00e1tskych lokusov v patogen\u00e9ze nesyndr\u00f3mov\u00fdch orofaci\u00e1lnych r\u00e1z\u0161tepov v popul\u00e1cii Slovenska.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e z \u00fastavu: \u0160alagovi\u010d \nDoba rie\u0161enia: 2014-2016<\/p>\nVEGA 1\/0724\/15: Novoobjaven\u00e9 genetick\u00e9 mut\u00e1cie v\u00a0etiopatogen\u00e9ze dyst\u00f3ni\u00ed: ich v\u00fdznam, prevalencia a manifest\u00e1cia <\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: RNDr. Viera Habalov\u00e1, PhD. \nDoba rie\u0161enia: 2015-2017<\/p>\nVEGA 1\/4231\/07: Vz\u0165ah polymorfizmu kandid\u00e1tskych g\u00e9nov k riziku vzniku, rozvoja a z\u00e1va\u017enosti chronickej ob\u0161truk\u010dnej choroby p\u013e\u00fac.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: RNDr. \u017didzik Jozef, PhD. \nDoba rie\u0161enia: 2007-2009<\/p>\nVEGA 1\/0864\/08: Riziko vzniku folikul\u00e1rneho lymf\u00f3mu vo vz\u0165ahu k polymorfizmom v g\u00e9noch pre DNA repair.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: prof. RNDr. J\u00e1n \u0160alagovi\u010d, PhD. \nDoba rie\u0161enia: 2008-2010<\/p>\nVEGA 1\/0368\/10: Sledovanie vplyvu genetick\u00e9ho pozadia pacientov s chronickou hepatit\u00eddou C na \u00faspe\u0161nos\u0165 interfer\u00f3novej lie\u010dby.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: doc. MUDr. P. Kristian, PhD \nZ\u00e1stupca ZR: RNDr. Viera Habalov\u00e1, PhD. \nDoba rie\u0161enia: 2010-2011<\/p>\nVEGA 1\/0690\/11: \u0160t\u00fadium hypermetyl\u00e1cie vybran\u00fdch g\u00e9nov u pacientov s n\u00e1dormi prostaty s cie\u013eom identifik\u00e1cie biomarkerov pre diagnostiku a prognostiku ochorenia.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: RNDr. Jana Halu\u0161kov\u00e1, PhD. \nDoba rie\u0161enia: 2011-2013<\/p>\nVEGA 1\/1132\/12: Identifik\u00e1cia biomarkerov vo vz\u0165ahu k efektivite terapie a progn\u00f3ze u pacientov s folikulov\u00fdm lymf\u00f3mom.<\/strong> \nDoba rie\u0161enia: 2012-2014 \nZodpovedn\u00fd rie\u0161ite\u013e: prof. MUDr. Elena T\u00f3thov\u00e1, PhD. \nZ\u00e1stupca ZR: RNDr. Lucia Klim\u010d\u00e1kov\u00e1, PhD.<\/p>\nProjekty rie\u0161en\u00e9 v spolupr\u00e1ci s \u00fastavmi a klinikami LF UPJ\u0160 a UNLP (zamestnanci \u00daLB s\u00fa spolurie\u0161ite\u013emi)<\/h3>\n VEGA 1\/0815\/14: Postkondicionovanie ako mo\u017en\u00fd sp\u00f4sob ochrany neur\u00f3nov v ischemizovanej mieche: \u0161t\u00fadium mechanizmov vyprovokovanej ischemickej tolerancie.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: doc. MVDr. Iveta Domor\u00e1kov\u00e1, PhD. \nDoba rie\u0161enia: 2014-2016<\/p>\nVEGA-1\/0389\/14: Sledovanie vz\u0165ahu variantov vybran\u00fdch kandid\u00e1tskych g\u00e9nov ateroskler\u00f3zy na z\u00e1va\u017enos\u0165 perif\u00e9rneho art\u00e9riov\u00e9ho obliteruj\u00faceho ochorenia doln\u00fdch kon\u010dat\u00edn u diabetikov 2. typu.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: MUDr. Miriam Koz\u00e1rov\u00e1, PhD. \nDoba rie\u0161enia: 2014-2016<\/p>\nVEGA 1\/0863\/15:\u00a0 Interakcia genetick\u00e9ho pozadia a chronickej intermitentnej hypoxie v patogen\u00e9ze kardiovaskul\u00e1rnych komplik\u00e1ci\u00ed ob\u0161truk\u010dn\u00e9ho sp\u00e1nkov\u00e9ho apnoe.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: MUDr. Pavol Joppa, PhD. \nDoba rie\u0161enia: 2015-2017<\/p>\nVEGA 1\/0027\/16:\u00a0 Sledovanie asoci\u00e1ci\u00ed vybran\u00fdch g\u00e9nov\u00fdch variantov s odpove\u010fou na lie\u010dbu or\u00e1lnymi antidiabetikami glipt\u00ednmi.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: prof. MUDr. Ivan Tk\u00e1\u010d, PhD. \nDoba rie\u0161enia: 2016-2018<\/p>\nVEGA 1\/0429\/17 : Indukcia ischemickej tolerancie v\u00a0mieche kr\u00e1lika vzdialen\u00fdm perkondicionovan\u00edm a\u00a0postkondicionovan\u00edm: \u0161t\u00fadium mechanizmov endog\u00e9nnel ochrany.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: RNDr. Marianna Dankov\u00e1, PhD. \nDoba rie\u0161enia: 2017-2019<\/p>\nEXTASY \u2013 Excelentn\u00fd t\u00edm pre v\u00fdskum ateroskler\u00f3zy\u2013 \u0161t\u00fadium vplyvu hypoxie na metabolick\u00e9 procesy od \u00farovne buniek, cez \u00farove\u0148 tkan\u00edv a org\u00e1nov po \u00farove\u0148 organizmu pacienta. <\/strong><\/p>\nVEGA 1\/4304\/07: Sledovanie efektu polymorfizmov kandid\u00e1tskych g\u00e9nov na vek manifest\u00e1cie diabetes mellitus 2. typu, <\/strong>hladiny rizikov\u00fdch faktorov ateroskler\u00f3zy a v\u00fdskyt makrovaskul\u00e1rnych komplik\u00e1ci\u00ed diabetu. \nZodpovedn\u00fd rie\u0161ite\u013e: prof. MUDr. Ivan Tk\u00e1\u010d, PhD. \nDoba rie\u0161enia: 2007-2009<\/p>\nVEGA 1\/0380\/10: Sledovanie vplyvu polymorfizmov kandid\u00e1tskych g\u00e9nov diabetes mellitus 2. typu na efekt lie\u010dby or\u00e1lnymi antidiabetikami zo skup\u00edn deriv\u00e1tov sulfonylurey a inhib\u00edtorov dipeptidyl-peptid\u00e1zy 4 (DPP-4).<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: Tk\u00e1\u010d Ivan, prof. MUDr., PhD. \nDoba rie\u0161enia: 2010-2011<\/p>\nVEGA1\/0525\/10: Poruchy fol\u00e1tov\u00e9ho metabolizmu v patogen\u00e9ze viacpo\u010detn\u00fdch malform\u00e1ci\u00ed.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: Behunov\u00e1 Jana, MUDr., PhD. \nDoba rie\u0161enia:2010-2011<\/p>\nVEGA 1\/0479\/10: G\u00e9nov\u00e9 polymorfizmy u pacientov s vazovag\u00e1lnou synkopou.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: prof. MUDr. Peter Mitro, PhD. \nDoba rie\u0161enia: 2010-2012<\/p>\nVEGA 1\/0112\/11: Sledovanie vz\u0165ahu polymorfizmov niektor\u00fdch kandid\u00e1tskych g\u00e9nov ateroskler\u00f3zy k angiograficky diagnostikovanej z\u00e1va\u017enosti koron\u00e1rnej choroby srdca u diabetikov a u pacientov bez diabetu.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: Javorsk\u00fd Martin, MUDr., PhD. \nDoba rie\u0161enia: 2011-2013<\/p>\nVEGA 1\/0715\/11: Molekulovo genetick\u00e1 diagnostika u det\u00ed s nefrotick\u00fdm syndr\u00f3mom.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: Podrack\u00e1 \u013dudmila, prof. MUDr., CSc. \nDoba rie\u0161enia: 2011-2013<\/p>\nAPVV-0134-11: \u00daloha hypoxie v aktiv\u00e1cii molekul\u00e1rnych dr\u00e1h asociovan\u00fdch so zv\u00fd\u0161en\u00fdm kardiovaskul\u00e1rnym rizikom u pacientov so sp\u00e1nkov\u00fdm apnoe a ich ovplyvnenie lie\u010dbou.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: prof. MUDr. Ru\u017eena Tk\u00e1\u010dov\u00e1 DrSc. \nDoba rie\u0161enia: 2011-2013<\/p>\nVEGA 1\/0340\/12: Sledovanie efektu polymorfizmov g\u00e9nov ovplyv\u0148uj\u00facich farmakokinetiku a farmakodynamiku metform\u00ednu na \u00fa\u010dinok lie\u010dby metform\u00ednom u pacientov s diabetom 2.typu.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: Tk\u00e1\u010d Ivan, prof. MUDr., PhD. \nDoba rie\u0161enia: 2012-2014<\/p>\nVEGA 1\/0111\/12:Vz\u0165ah chronickej intermitentnej hypoxie k funkcii endotelu a k aktiv\u00e1cii z\u00e1palov\u00fdch sign\u00e1lnych dr\u00e1h v tukovom tkanive u pacientov so sp\u00e1nkov\u00fdm apnoe.<\/strong> \nZodpovedn\u00fd rie\u0161ite\u013e: prof. MUDr. Ru\u017eena Tk\u00e1\u010dov\u00e1 DrSc. \nDoba rie\u0161enia: 2012-2014<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":29612,"menu_order":3,"template":"","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[],"tags":[],"tax_aktuality":[],"class_list":["post-29615","cpt_ustav","type-cpt_ustav","status-publish","hentry"],"acf":{"acf_link_na_externy_obsah":""},"yoast_head":"\nProjekty - Lek\u00e1rska fakulta | UPJ\u0160<\/title>\n \n \n \n \n \n \n \n \n \n \n \n\t \n