{"id":34665,"date":"2021-09-08T11:47:28","date_gmt":"2021-09-08T11:47:28","guid":{"rendered":"https:\/\/www.upjs.sk\/lekarska-fakulta\/pracoviska\/laboratorium-bunkovych-interakcii\/"},"modified":"2022-11-13T22:28:31","modified_gmt":"2022-11-13T21:28:31","slug":"laboratorium-bunkovych-interakcii","status":"publish","type":"cpt_pracoviska","link":"https:\/\/www.upjs.sk\/lekarska-fakulta\/pracoviska\/laboratorium-bunkovych-interakcii\/","title":{"rendered":"Laborat\u00f3rium bunkovych interakci\u00ed"},"content":{"rendered":"\n\n\n\n
Trieda SNP 1, 040 11 Ko\u0161ice<\/td>\n\"English<\/a><\/td>\n<\/tr>\n
\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Predmetom v\u00fdskumu LBI je \u0161t\u00fadium bunkov\u00fdch interakci\u00ed zapojen\u00fdch do regul\u00e1cie mikroprostredia n\u00e1dorov a r\u00e1n s mo\u017enos\u0165ou ich terapeutick\u00e9ho ovplyvnenia. LBI je priamo prepojen\u00e9 s Refer\u00e1tom biomedic\u00ednskeho v\u00fdskumu V\u00daSCH, a.s. a \u00fazko spolupracuje s viacer\u00fdmi dom\u00e1cimi a zahrani\u010dn\u00fdmi v\u00fdskumn\u00fdmi skupinami.<\/p>\n

https:\/\/www.upjs.sk\/lekarska-fakulta\/centrum-vyskumu\/medipark\/aktuality\/22466\/<\/a><\/p>\n

Medzi dom\u00e1ce spolupracuj\u00face pracovisk\u00e1 patr\u00ed najm\u00e4 \u00dastav farmakol\u00f3gie UPJ\u0160 LF v Ko\u0161iciach a Katedra farmakogn\u00f3zie a botaniky UK FaF v Bratislave. Zo zahrani\u010dn\u00fdch pracov\u00edsk je zabehnut\u00e1 dlhodob\u00e1 spolupr\u00e1ca s laborat\u00f3riom Univ.-Prof. Dr. Dr.h.c. Hansa-Joachima Gabiusa z Univerzity Ludwiga-Maximili\u00e1na v Mn\u00edchove a laborat\u00f3riom prof. MUDr. Karla Smetanu, DrSc. z Anatomick\u00e9ho \u00fastavu 1. LF UK, ktor\u00e1 je zameran\u00e1 na glykobiol\u00f3giu a bunkov\u00e9 interakcie v n\u00e1doroch a ran\u00e1ch. V poslednej dobe sa na\u0161e pracovisko zap\u00e1ja aj do v\u00fdvoja akt\u00edvnych a antibakteri\u00e1lnych kryt\u00ed r\u00e1n, a to najm\u00e4 s Klinikou pop\u00e1leninov\u00e9 medic\u00edny 3. LF UK a FNKV v Prahe, skupinou Ing. Dominika Rejmana, CSc. z \u00dastavu organick\u00e9 chemie a\u00a0biochemie AV\u010cR a Laborato\u0159\u00ed p\u0159\u00edpravy nanovl\u00e1ken a nanopovrch\u016f prof. RNDr. Davida Luk\u00e1\u0161a, CSc. z TUL v\u00a0Liberci.<\/p>\n

\u00a0<\/p>\n

Samostatn\u00fd vedeck\u00fd pracovn\u00edk<\/strong>
\nRNDr. Peter G\u00e1l, PhD., MBA<\/p>\n

Doktorandi<\/strong>
\nMgr. Nikola Melegov\u00e1
\nMgr. Miriam Gurb\u00e1\u013eov\u00e1
\nMgr. Luk\u00e1\u0161 Urban<\/p>\n

\u00a0<\/p>\n

Vybran\u00e9 publik\u00e1cie<\/strong><\/p>\n

    \n
  1. Zajicek R, Kubok R, Petrova N, Tokarik M, Matouskova E, Gal P. Complex approach of skin repair in extensively burned child: bilayer Integra\u00ae and skin grafting facilitated by non-cultured autologous skin cells and Xe-Derma\u00ae. J Wound Care. in press<\/li>\n
  2. Michalov\u00e1 Z, \u010coma M, Ki\u010dov\u00e1 M, Gabzdilov\u00e1 J, Dedinsk\u00e1 K, Guman T, H\u00e1jikov\u00e1 M, Veselinyov\u00e1 D, Giertlova M, G\u00e1l P, \u0160ari\u0161sk\u00fd M. Overexpression of Galectin-3 in Chronic Lymphocytic Leukemia Is Associated With 17p Deletion: A Short Report. Anticancer Res. 2019 Jun;39(6):2805-2810.<\/li>\n
  3. F\u00e1ber L, Kov\u00e1\u010d I, Mitrengov\u00e1 P, Novotn\u00fd M, Varinsk\u00e1 L, Vasilenko T, Kello M, \u010coma M, Kuruc T, Petrov\u00e1 K, Mil\u00e1\u010dkov\u00e1 I, Kuczmannov\u00e1 A, Per\u017ee\u013eov\u00e1 V, Mi\u017e\u00e1kov\u00e1 \u0160, Dosedla E, Sabol F, Luczy J, Nagy M, Majern\u00edk J, Ko\u0161\u010do M, Mu\u010daji P, G\u00e1l P. Genistein Improves Skin Flap Viability in Rats: A Preliminary In Vivo and In Vitro Investigation. Molecules. 2018 Jul 4;23(7). pii: E1637.<\/li>\n
  4. Zivicova V, Gal P, Mifkova A, Novak S, Kaltner H, Kolar M, Strnad H, Sachova J, Hradilova M, Chovanec M, Gabius HJ, Smetana K Jr, Fik Z. Detection of Distinct Changes in Gene-expression Profiles in Specimens of Tumors and Transition Zones of Tenascin-positive\/-negative Head and Neck Squamous Cell Carcinoma. Anticancer Res. 2018 Mar;38(3):1279-1290.<\/li>\n
  5. G\u00e1l P, Varinsk\u00e1 L, F\u00e1ber L, Nov\u00e1k \u0160, Szabo P, Mitrengov\u00e1 P, Mirossay A, Mu\u010daji P, Smetana K. How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair. Molecules. 2017 Oct 26;22(11). pii: E1818.<\/li>\n
  6. Per\u017ee\u013eov\u00e1 V, Sabol F, Vasilenko T, Novotn\u00fd M, Kov\u00e1\u010d I, Slez\u00e1k M, \u010eurk\u00e1\u010d J, Holl\u00fd M, Pil\u00e1tov\u00e1 M, Szabo P, Varinsk\u00e1 L, \u010criepokov\u00e1 Z, Ku\u010dera T, Kaltner H, Andr\u00e9 S, Gabius HJ, Mu\u010daji P, Smetana K Jr, G\u00e1l P. Pharmacological activation of estrogen receptors-\u03b1 and -\u03b2 differentially modulates keratinocyte differentiation with functional impact on wound healing. Int J Mol Med. 2016 Jan;37(1):21-8.<\/li>\n
  7. Kov\u00e1\u010d I, \u010eurk\u00e1\u010d J, Holl\u00fd M, Jakub\u010dov\u00e1 K, Per\u017ee\u013eov\u00e1 V, Mu\u010daji P, \u0160vajdlenka E, Sabol F, Leg\u00e1th J, Bel\u00e1k J, Smetana K Jr, G\u00e1l P. Plantago lanceolata L. water extract induces transition of fibroblasts into myofibroblasts and increases tensile strength of healing skin wounds. J Pharm Pharmacol. 2015 Jan;67(1):117-25.<\/li>\n
  8. Valach J, F\u00edk Z, Strnad H, Chovanec M, Plz\u00e1k J, Cada Z, Szabo P, S\u00e1chov\u00e1 J, Hroudov\u00e1 M, Urbanov\u00e1 M, Steffl M, Pa\u010des J, Maz\u00e1nek J, Vl\u010dek C, Betka J, Kaltner H, Andr\u00e9 S, Gabius HJ, Kodet R, Smetana K Jr, G\u00e1l P, Kol\u00e1\u0159 M. Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: increased expression of galectin-1 and induction of poor prognosis factors. Int J Cancer. 2012 Dec 1;131(11):2499-508.<\/li>\n
  9. Novotn\u00fd M, Vasilenko T, Varinsk\u00e1 L, Smetana K Jr, Szabo P, Sari\u0161sk\u00fd M, Dvo\u0159\u00e1nkov\u00e1 B, Moj\u017ei\u0161 J, Bobrov N, Toporcerov\u00e1 S, Sabol F, Matthews BJ, G\u00e1l P. ER-\u03b1 agonist induces conversion of fibroblasts into myofibroblasts, while ER-\u03b2 agonist increases ECM production and wound tensile strength of healing skin wounds in ovariectomised rats. Exp Dermatol. 2011 Sep;20(9):703-8.<\/li>\n
  10. Dvo\u0159\u00e1nkov\u00e1 B, Szabo P, Lacina L, Gal P, Uhrova J, Zima T, Kaltner H, Andr\u00e9 S, Gabius HJ, Sykova E, Smetana K Jr. Human galectins induce conversion of dermal fibroblasts into myofibroblasts and production of extracellular matrix: potential application in tissue engineering and wound repair. Cells Tissues Organs. 2011;194(6):469-80.<\/li>\n<\/ol>\n","protected":false},"author":1,"featured_media":16416,"parent":0,"menu_order":10,"template":"","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}"},"class_list":["post-34665","cpt_pracoviska","type-cpt_pracoviska","status-publish","has-post-thumbnail","hentry"],"acf":{"acf_link_na_externy_obsah":""},"yoast_head":"\nLaborat\u00f3rium bunkovych interakci\u00ed - Lek\u00e1rska fakulta | UPJ\u0160<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.upjs.sk\/lekarska-fakulta\/pracoviska\/laboratorium-bunkovych-interakcii\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Laborat\u00f3rium bunkovych interakci\u00ed - Lek\u00e1rska fakulta | UPJ\u0160\" \/>\n<meta property=\"og:description\" content=\"Trieda SNP 1, 040 11 Ko\u0161ice \u00a0 Predmetom v\u00fdskumu LBI je \u0161t\u00fadium bunkov\u00fdch interakci\u00ed zapojen\u00fdch do regul\u00e1cie mikroprostredia n\u00e1dorov a r\u00e1n s mo\u017enos\u0165ou ich terapeutick\u00e9ho ovplyvnenia. 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